This technique delivers high doses of chemotherapy drugs directly to the tumor through a catheter inserted into an artery. This can increase the effectiveness of the drugs and reduce the side effects on the rest of the body. Arterial infusion chemotherapy can be performed with or without a port system, which is a device implanted under the skin that allows repeated access to the artery. It can be combined with other treatments, such as immunotherapy or targeted therapy, to enhance the anti-tumor response.