The term "nanoknife" typically refers to a medical device known as Irreversible Electroporation (IRE) or NanoKnife System. This innovative technology is used for minimally invasive surgical procedures, particularly in the treatment of cancer. The NanoKnife System employs electrical pulses to create irreversible pores in cell membranes, leading to cell death. It is often utilized in the ablation of tumors, where precision and minimal damage to surrounding tissues are crucial.
The NanoKnife consists of thin electrodes that are carefully placed around the targeted tumor or lesion. Once in position, controlled electrical pulses are delivered through these electrodes. These pulses create nanopores in the cell membranes, disrupting the cellular structure and causing apoptosis, or programmed cell death. The advantage of this technology lies in its ability to selectively target cancerous cells while preserving nearby healthy tissues, nerves, and blood vessels.
One significant application of the NanoKnife is in the treatment of tumors that are challenging to reach with traditional surgical methods or where conventional treatments like radiation therapy may pose risks to surrounding structures. The precise nature of NanoKnife procedures makes it suitable for tumors near critical organs or structures.
Overall, the NanoKnife represents a cutting-edge approach to cancer treatment, offering a promising alternative for patients facing complex cases where traditional therapies may not be as effective or suitable. Its minimally invasive nature, coupled with its ability to spare healthy tissues, positions the NanoKnife as a valuable tool in the evolving landscape of medical technology and oncological care.